New Publication: Guidelines in Quantitative Cerebral Perfusion MRI with ASL

In a significant advancement in the field of medical imaging, a recent publication in the esteemed journal Magnetic Resonance in Medicine introduces comprehensive guidelines for quantitative cerebral perfusion MRI using multi-timepoint arterial spin labeling (ASL). The paper, titled "Recommendations for quantitative cerebral perfusion MRI using multi-timepoint arterial spin labeling: Acquisition, quantification, and clinical applications", serves as a crucial resource for both researchers and clinicians interested in cerebral perfusion imaging.

The article includes contributions from our CEO at Gold Standard Phantoms, Prof. Xavier Golay, an honorary professor of the University College of London's Institute on Neurology and a revered figure in MRI research. Prof. Golay's involvement underscores the integration of academic expertise and industry innovation, driving forward the capabilities and applications of MRI technology.


Gold Standard Phantoms’ QASPER: A Benchmark in MRI Calibration

Central to enhancing the precision and reliability of MRI perfusion measurements is the innovative QASPER phantom from Gold Standard Phantoms. The QASPER phantom, or Quantitative Arterial Spin Labeling Perfusion Reference, is designed to simulate the delivery of arterial blood to an organ. This technology serves as a calibration and quality assurance standard, ensuring that MRI perfusion measurements are both controlled and reproducible. QASPER's design enables it to mimic the complex physiological process of blood flow to the brain, providing a consistent and standardized reference that can be used across different MRI machines and settings. This capability is crucial for advancing the clinical applications of MRI, particularly in diagnosing and monitoring diseases that affect cerebral blood flow, such as stroke and dementia.

The guidelines proposed in the publication, combined with the application of the QASPER phantom, pave the way for significant enhancements in the field of MRI. These developments promise to improve the accuracy of diagnosing neurological conditions and enable a more detailed understanding of cerebrovascular diseases. By standardizing ASL MRI procedures, researchers and clinicians can confidently compare studies and progress toward more personalized medicine approaches. The collaboration between academia and industry, exemplified by Prof. Golay’s co-authorship and the technological innovation of QASPER, highlights an exciting era of improved diagnostic tools and refined imaging techniques. With these advancements, the medical community steps closer to offering better, more precise patient care and fostering further research in cerebral perfusion.

Join us at ISMRM 2024 (booth C04) from May 4th to May 9th in Singapore,

where we introduce QASPER 2.0 with lots of new improvements!


Explore more about how our new QASPER is setting the gold standard in MRI perfusion measurements on our QASPER product page.

Read the full publication on Wiley Online Library website here: https://onlinelibrary.wiley.com/doi/epdf/10.1002/mrm.30091

We're thrilled to announce that Gold Standard Phantoms will be showcasing our groundbreaking MRI technologies at the upcoming Ampere Investor + Pitching Event on March 26th from 2–5 PM at Electric Works.


GSP stands at the forefront of a ground-breaking evolution in medical imaging, embodying precision, reliability, and innovation. Founded on the principle that accurate diagnosis is the cornerstone of effective treatment, GSP introduced over the last 9 years an unparalleled suite of quality assurance and calibration devices, called phantoms, designed to revolutionise the field of MRI. These phantoms, meticulously engineered to simulate the physical properties of human tissue, offer a new benchmark in the validation and standardisation of imaging techniques across the whole MRI field.

GSP’s has recently developed the first-ever one-stop-shop calibration technology. Combining embedded phantoms with calibration software provided through a subscription as software as a medical device (SaaMD). Early results from this ground-breaking technology received a lot of interest from the major OEMs in this sector at the recent European Congress of Radiology held in Vienna at the beginning of March.


Why GSP?

Precision and Reliability:

Our phantoms ensure consistent and accurate imaging, essential for effective diagnosis and treatment.

Innovation: 

The first-ever one-stop-shop calibration technology, combining embedded phantoms with calibration software, has already caught the attention of major OEMs.

Expertise: 

Our co-founders, Prof. Xavier Golay, Dr. Aaron Oliver-Taylor, and Dr. Tom Hampshire, bring over 50 years of combined experience in MRI technology.


With over 125 million MRI scans performed annually worldwide, GSP is poised to capture a significant market share with our potentially revolutionary technology. Globally over 5000 MRI machines are bought yearly with an estimated 50,000 currently installed in OECD countries. With a global market worth $5.2B in 2023 and a CAGR of 5%, GSP is positioned to capture a sizable share with its potentially revolutionary technology.

 


GSP originated in London but has relocated to Sheffield, following an emerging trend of companies migrating to the secret startup capital of the UK.

For GSP, Sheffield was the obvious choice given its access to two major universities, facilities such as the Advanced Manufacturing Research Centre (AMRC), and several major teaching hospitals.


Co-founders Prof. Xavier Golay, Dr. Aaron Oliver-Taylor, and Dr. Tom Hampshire, initially crossed paths in their separate departments at University College London. Having worked together since 2014, the team combined comes with more than 50 years of experience in the field.

Xavier Golay, co-founder & CEO, started his PhD in MRI in 1994 and pursued a career that brought him from Switzerland to UCL as Professor of MR Physics, via Johns Hopkins in the USA and Philips Healthcare in Singapore. In June 2023, he decided that he could no longer sustain both academic and commercial activities and gave up his post at UCL to take over the helm of the company full-time.

Aaron Oliver Taylor, Co-Founder & CTO, finished his PhD in MRI in 2012 at UCL, where he met Xavier and first talked about developing calibration devices for MRI, which eventually led to the foundation of GSP. Aaron is an amazing multitasker, with a breadth of knowledge spanning chemistry, electronics, imaging, and hardware development. He has worked at the company as CTO since its inception.

Tom Hampshire, Co-Founder & CIO, is a computer scientist and software engineer, with a PhD in Medical Image Computing (2013). Tom has been the driving force behind the software development of the company. With such skills, he was a natural third founder to the team, helping shape the company into what it has become today.


Join us at the Ampere X STP Investor Event + Pitching in Sheffield on March 26th, from 2-5 PM at Electric Works. Don't miss this opportunity to see GSP's pitch and learn more about how we're shaping the future of medical imaging.


Investor link: https://www.eventbrite.co.uk/e/ampere-x-stp-pitching-day-for-investors-tickets-849498150837 

Founder link: https://ampere.events/event/ampere-events-x-stp-investor-event-pitching/

Electric Works: 3 Concourse Way, Sheffield City Centre, Sheffield S1 2BJ

GSP are excited to announce our new partnership with Quibim. Combining best in class algorithms with sound metrology! Together, we are committed to ensuring high quality MRI data for use in generalizable AI.

As a company leading the way in the implementation of quantitative MRI, Gold Standard Phantoms are excited to announce our new partnership with Quibim. One of the European leaders in the field of artificial intelligence (AI) and medical imaging, aiming to revolutionise drug development and patient care pathways.

The use of high quality data for AI algorithms is highly important to increase its power in these areas, therefore it is of paramount importance that good metrological practices are used to ensure traceability back to reference standards. Gold Standard Phantoms will work together with Quibim to facilitate the use of imaging biomarkers in the clinics. We look forward to the opportunities this collaboration will bring in the medical field by driving forward quantitative measurements in artificial intelligence.

Quibim develops quantitative biomarkers, companion diagnostics and other imaging tools for systems biology applications, from immuno-oncology to neurology. Quibim partners with pharma industry and large real-world data players.

It is also the reference imaging platform behind for the largest internal research consortiums and biobanks in cancer.

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